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目的了解广东地区不孕症妇女TORCH感染率及不同年龄段不孕症妇女TORCH感染分布情况。方法对2012年1月-2015年6月来我院就诊的10 531例不孕症妇女采用酶联免疫法(ELISA)进行TORCH IgM抗体检测。结果广东地区不孕症妇女TORCH IgM抗体阳性率从高至低分别是巨细胞病毒1.7%、单纯疱疹病毒1.1%、风疹病毒1.1%及弓形虫0.7%,TORCH总的感染率为4.6%。在不同年龄段感染特点各有不同,其中单纯疱疹病毒的感染,在20~25岁组阳性率最低为0.7%,26~30岁组阳性率为1.1%,31~35岁组阳性率为1.0%,36~40岁组阳性率为1.8%,大于40岁组阳性率为2.7%,单纯疱疹病毒的感染有随着年龄增大感染率增高的趋势;在不同年龄段弓形虫、风疹病毒和巨细胞病毒的感染无统计学差异。结论不孕症人群中存在一定比例的TORCH感染,要广泛进行卫生宣传教育,减少由TORCH感染引起的不良妊娠的发生。
Objective To understand the prevalence of TORCH infection and the distribution of TORCH in infertile women of different ages in Guangdong area. Methods TORCH IgM antibody was detected by enzyme-linked immunosorbent assay (ELISA) in 10 531 infertile women who came to our hospital from January 2012 to June 2015. Results The positive rates of TORCH IgM antibodies in infertile women in Guangdong from high to low were 1.7% of cytomegalovirus, 1.1% of herpes simplex virus, 1.1% of rubella virus and 0.7% of toxoplasma respectively. The total infection rate of TORCH was 4.6%. Infections at different ages have different characteristics, of which herpes simplex virus infection in the 20-25 years old group the lowest positive rate of 0.7%, 26-30 years old group was 1.1% positive, 31-35 years old group was 1.0 %. The positive rate was 1.8% in 36-40 years old group and 2.7% in those older than 40 years old group. The infection rate of herpes simplex virus was increased with age. Toxoplasma gondii, rubella virus and Cytomegalovirus infection was not statistically different. Conclusion There is a certain proportion of TORCH infection in infertile population, and public health education should be widely carried out to reduce the incidence of adverse pregnancy caused by TORCH infection.