苯妥英钠为二苯乙内酰脲类，抑制异位电活动的扩散，是有效的抗癫痫药，适用于癫痫大发作，但其不良反应时有发生，甚至会发生严重的毒性反应，应引起医生和药学人员的注意。由于苯妥英钠治疗指数窄（１０～２０μｇ·ｍｌ－１），个体差异大，为零级药代动力学药物，在应用一 Phenytoin sodium is diphenylhydantoin class, inhibit the proliferation of ectopic electrical activity is effective anti-epileptic drugs, suitable for epileptic seizures, but the adverse reactions occur from time to time, and even serious toxic reactions should be caused Doctor and pharmacy staff’s attention. Because phenytoin treatment index is narrow (10 ~ 20μg · ml-1), individual differences, for the zero-level pharmacokinetic drugs, in the application of a