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目的了解医院重症监护病房(ICU)支原体感染情况。方法入选2007年12月~2008年9月ICU住院患者共65例,对每例患者取其各种标本,进行肺炎支原体、解脲脲支原体、穿透支原体、发酵支原体培养,对培养阳性标本进行生化及PCR方法鉴定。结果65份标本,血培养检出肺炎支原体8株(25.8%)、解脲脲支原体1株(5.6%);咽拭子培养检出肺炎支原体23株(74.2%);泌尿生殖道分泌物培养检出解脲脲支原体17株(94.4%),未检出穿透支原体、发酵支原体。结论ICU患者支原体感染情况严重,且存在与细菌等混合感染现象,在选用抗菌药物时应考虑抗菌谱覆盖支原体。
Objective To understand the prevalence of Mycoplasma infection in intensive care unit (ICU) in hospitals. Methods A total of 65 inpatients with ICU from December 2007 to September 2008 were enrolled in this study. Specimens of each patient were collected for mycoplasma pneumonia, Ureaplasma urealyticum, Mycoplasma pneumoniae and Mycoplasma fermentum, and positive samples were cultured Biochemistry and PCR identification. Results Sixty-five specimens were obtained from blood culture, eight strains of Mycoplasma pneumoniae (25.8%) and one strain of Ureaplasma urealyticum (5.6%) were detected in blood culture. Throat swabs detected 23 strains of Mycoplasma pneumoniae (74.2% Seventeen strains (94.4%) of U. urealyticum were detected. Mycoplasma and Mycoplasma fermentum were not detected. Conclusion ICU patients with severe mycoplasma infection, and the existence of mixed infection with bacteria and other phenomena, antibiotics should be considered in the selection of antimicrobial spectrum covering mycoplasma.