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目的探讨米索前列醇直肠给药减少腹腔镜下子宫肌瘤切除术术中出血的临床应用效果。方法 130例行腹腔镜下子宫肌瘤切除术的患者,按米索前列醇给药方式分为治疗组和对照组,各65例。治疗组为直肠给药,对照组为口服给药。观察两组手术时间、术中出血量、术后肛门排气时间及住院时间。结果两组均顺利完成手术,且术后未出现明显并发症。治疗组手术时间为(65.26±6.42)min、术中出血量为(50.18±12.01)ml均少于对照组的(70.57±7.47)min、(60.08±13.71)ml,差异具有统计学意义(P<0.05);两组术后肛门排气时间、住院时间比较差异无统计学意义(P>0.05)。结论米索前列醇直肠给药减少腹腔镜下子宫肌瘤切除术术中出血的临床应用效果明显,临床可推广应用。
Objective To investigate the clinical effect of misoprostol rectal administration to reduce bleeding during laparoscopic myomectomy. Methods 130 cases of laparoscopic myomectomy patients, according to misoprostol administration were divided into treatment group and control group, 65 cases each. The treatment group was rectally administered and the control group was orally administered. The operation time, intraoperative blood loss, postoperative anal exhaust time and hospital stay were observed. Results The two groups were successfully completed surgery, and no significant postoperative complications. The operation time of the treatment group was (65.26 ± 6.42) min, and the blood loss was (50.18 ± 12.01) ml less than the control group (70.57 ± 7.47) min, (60.08 ± 13.71) ml, the difference was statistically significant (P <0.05). There was no significant difference in anal exhaust time and hospital stay between the two groups (P> 0.05). Conclusion The clinical application of misoprostol rectal administration to reduce laparoscopic bleeding during myomectomy is effective and can be applied clinically.