男,57岁。因精神错乱伴尿潴留10天入院。1981年起食欲不振,顽固性腹泻,体重下降,常尿失禁,闻水声即生尿意。1983年起四肢手套袜套样麻木刺痛,双腿无力,肌萎缩,常摔跤,右腿尤重。1984年以来每逢夏季双前臂及前额部大片对称性红斑灼痛脱皮,由红变棕黄色然后复常。伴口痛,舌炎发红后变黑,记忆力差,思维缓慢。长期饮酒0.25～0.5kg/日。 Male, 57 years old. Due to insanity with urinary retention 10 days admitted. Loss of appetite since 1981, intractable diarrhea, weight loss, urinary incontinence, smell the sound of urine that means. Since 1983, limbs gloves socks numb stinging, weak legs, muscle atrophy, often wrestling, particularly right leg. Since the summer of 1984 both forearms and forehead large symmetrical erythema burning pain peeling, reddish brown and then normal. With mouth pain, glossitis reddish black, poor memory, slow thinking. Long-term drinking 0.25 ~ 0.5kg / day.