论文部分内容阅读
鼻咽癌(NPC)是我国最常见的头颈部肿瘤之一,高发于南方.NPC的病因复杂,发病机制不清,虽对放疗较为敏感,但其治疗仍面临复发和转移的高风险.EB病毒(Epstein-Barr virus)是NPC的高危因素,与NPC密切相关,目前是NPC形成机制的研究重点.本文从免疫应答及EB病毒相关产物两方面就EB病毒在NPC发病机制中的免疫学作用作一综述,并初步探讨免疫治疗在NPC的应用.“,”Nasopharyngeal carcinoma( NPC) is one of the most common head and neck neoplasm in southern China. However, the pathogenesis and etiology of NPC remain unclear. NPC is sensitive to radiotherapy, but the high risk of relapse and metastasis are challenges. Epstein-Barr virus is the most important high risk factor of NPC, which has been the theme to explore the pathogenesis of NPC in nowadays. In order to reveal the immunological effects of EB virus in the pathogenesis of NPC, the relevance of immune re-sponse and EB virus related products, as well as the application of immune therapy for NPC will be reviewed in this article.