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目的分析和总结大理地区广州管圆线虫病的临床特点及流行现状。方法通过查阅有关广州管圆线虫病的文献资料,结合本院接诊病例,总结了2007-2013年大理地区广州管圆线虫病的病例特点,并从广州管圆线虫的自然疫源地、中间宿主及终末宿主等几个方面分析大理地区广州管圆线虫病的流行现状及常用诊断技术。结果大理地区共有2次广州管圆线虫病流行,多次散发,累计报告77例病例,男性41例,女性36例,主要以白族(占68.8%)为主;临床以头痛和脑脊液中嗜酸性粒细胞增高为主,83.1%患者有进食生食史。结论大理地区广州管圆线虫病得到了控制,但仍在一定范围内流行,其主要通过进食生螺肉而感染。接触史和脑脊液中嗜酸性粒细胞增高仍是目前广州管圆线虫病诊断的主要依据,分子生物学诊断尚待进一步研究。
Objective To analyze and summarize the clinical features and prevalence status of angiostrongylus cantonensis in Dali area. Methods By reviewing the literature about angiostrongyliasis in Guangzhou and the case of admissions in our hospital, the characteristics of angiostrongyliasis in Guangzhou from 2007 to 2013 were summarized. From the natural foci of Aralia elata, Host and terminal host analysis of several aspects of the epidemic situation and commonly used diagnostic techniques of angiostrongyliasis in Guangzhou. Results A total of 77 cases of Gallstone nematodes were reported in Dali area. There were 77 cases in total, including 41 males and 36 females, mainly from Bai (68.8%). Headache and eosinophilic Granulocytosis mainly, 83.1% of patients have eating raw food history. Conclusion The angiostrongylus cantonensis has been controlled in Dali, but it is still prevailing within a certain range. It is mainly infected by eating raw snail. History of exposure and cerebrospinal fluid eosinophilia is still the main basis for the diagnosis of angiostrongyliasis in Guangzhou, molecular biology diagnosis remains to be further studied.