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因用药引起的发热即称药物热,在发热性疾患的鉴别诊断中不能忽略此症。据国外报道,用药引起的不良反应,住院病人约占10%,门诊病人占2.5%,而发热作为唯一的或最突出的临床特征,在不良反应中约占3～5%。临床上常不能及时作出此诊断,致使许多病人接受多种不必要的检查及治疗。一、引起药物热的药物几乎任何药物均可引起药物热,大体可分为三类:1.最常见的:有两性霉素 B、巴比土酸盐、青霉素类、硫酸奎尼丁、抗组织胺药、苯妥因钠、水杨酸钠、甲基多巴、普鲁卡因酰胺、磺胺类等。
Due to drug-induced fever that drug fever, fever in the differential diagnosis of disease can not be ignored in this disease. According to foreign reports, drug-induced adverse reactions, about 10% of inpatients, outpatients 2.5%, and fever as the only or most prominent clinical features, accounting for about 3 to 5% of adverse reactions. Clinically often can not make this diagnosis in time, resulting in many patients to accept a variety of unnecessary examination and treatment. First, the drug caused by hot drugs Almost any drug can cause drug fever can be broadly divided into three categories: 1. The most common: with amphotericin B, barbiturates, penicillins, quinidine sulfate, anti Histamine drugs, phenytoin sodium, sodium salicylate, methyldopa, procainamide, sulfonamides and so on.