论文部分内容阅读
补中益气口服液(以下简称口服液)的方剂组成与传统中成药补中益气丸(以下简称丸剂)相同,均由黄芪、党参、甘草、白术、当归、柴胡、升麻、陈皮组成。具有补中益气,升阳举陷等功效。由于丸剂有崩解差、生物利用度不高、服用不便等缺点。因此,湖州制药厂将其改为口服液,以求更好地发挥疗效。本实验对该厂研制的口服液与传统的丸剂进行了部分药效与急性毒性的对比研究,现将结果简要报告如下:一、实验材料1.动物 NIH 系小鼠18—22克,雌雄兼用。Wistar 系大鼠250克—300克,雌雄兼用。雌性未孕成熟家兔。
The formula of Buzhong Yiqi Oral Liquid (hereinafter referred to as oral solution) is the same as traditional Chinese medicine Buzhong Yiqi Pill (hereinafter referred to as pill). Both are composed of Radix Astragali, Codonopsis Pilosula, Radix Glycyrrhizae, Atractylodes Rhizome, Angelica, Bupleurum, Cimicifuga, Citrus composition. With Buzhong Yiqi, Shengyang lift traps and other effects. Pills have disadvantages such as poor disintegration, low bioavailability, and inconvenience of taking. Therefore, Huzhou Pharmaceutical Factory changed it to oral solution in order to achieve better efficacy. In this experiment, a comparative study on the efficacy and acute toxicity of oral liquids and conventional pills developed in the factory was conducted. The results are briefly reported as follows: 1. Experimental materials 1. Animals NIH mice 18-22 g, both male and female . Wistar rats are 250 grams to 300 grams, both male and female. Females are not mature pregnant rabbits.