The hazelnut weevil (Curculio dieckmanni Faust.) is a major pest of Asian hazel (Corylus heterophylla Fisch.) in China.Dead hazelnut weevil larvae were exam-ined and the associated pathogenic bacterium was identified as Serratia marcescens Bizio.This significantly shortened the lifespan of hazelnut weevil.Larval weight was reduced as a function of S.marcescens concentration and exposure time.The structure of infected midgut cells was altered,with necrosis of the wall tissues and many cells becoming dislodged,creating cavities.The S.marcencens strain inhib-ited digestive enzyme activity and protective enzymes in the midgut of adult hazelnut weevil.Inhibition on S.mar-cencens strain increased with treatment time.S.marcescens directly destroyed the midgut cells and interfered with diges-tive and protective enzymes.This decreased the food intake and increased mortality of hazelnut weevil.S.marcescens appears to be an effective bacterium for the control of hazel-nut weevil but requires further study,including biological formulation development and field application.