梅毒是梅毒螺旋体(treponema pallidum,TP)感染所致的一种慢性性传播疾病,神经梅毒系由TP感染人体后出现的大脑、脑膜或脊髓损害的一组临床综合征~([1]),未经治疗的早期梅毒患者约10%可发展为神经梅毒~([2])。梅毒性脊髓炎是神经梅毒的一种,是TP累及脊膜引起的炎症反应,是梅毒性神经损害的早期表现,多发生于TP感染后2~10年,表现为急性或亚急性横贯性脊髓损害,如下肢瘫痪或 Syphilis is a chronic sexually transmitted disease caused by the infection of treponema pallidum (TP), a group of clinical syndromes of brain, meningeal or spinal cord injury caused by TP infection in the human body. [1] About 10% of untreated early syphilis can develop neurosyphilis ~ ([2]). Syphilitic myelitis is a kind of neurosyphilis, TP is involved in the inflammatory reaction caused by the meninges, is an early manifestation of syphilitic nerve damage, occurred in 2 to 10 years after TP infection, manifested as acute or subacute traverse spinal cord Damage, such as paralysis of lower limbs or