目的　探讨腹腔镜手术中的腹压增高导致的心功能及血液动力学的变化。方法　用腹腔内快速注入空气的方法制造 7头乳猪急性腹压增高的模型。在腹压为基础值 7.5、15及 30mmHg时分别测量心输出量 ,左、右心房压 ,腹部下腔静脉压及心包压。结果　心输出量在轻度腹压增高时增加 ,当腹压超过 15mmHg时下降。腹压轻度增高时右心房压与下腔静脉压平行增高 ,而超过 15mmHg时 ,右心房压与下腔静脉压呈分离变化 ,右心房压停止增高。左心房透壁压和右心房透壁压与心输出量之间的变化关系明显不同。结论　腹腔镜手术中的腹压增高导致的心功能变化是一个复杂过程 ,不仅与气腹压力的大小有关 ,而且与机体所处的血液动力学状态相关 Objective To investigate the changes of cardiac function and hemodynamics caused by the increase of abdominal pressure in laparoscopic surgery. Methods Rapid intra-abdominal injection of air method for the manufacture of 7 piglets acute abdominal pressure increased model. Cardiac output, left and right atrial pressure, abdominal vena cava pressure and pericardial pressure were measured at abdominal pressure of 7.5, 15 and 30 mmHg, respectively. Results Cardiac output increased with mild increase in abdominal pressure and decreased when abdominal pressure exceeded 15 mmHg. When the abdominal pressure was mildly elevated, the right atrial pressure increased in parallel with the pressure of the inferior vena cava. When the pressure was over 15mmHg, the right atrial pressure and the pressure of the inferior vena cava separated and changed and the right atrial pressure stopped increasing. The relationship between left atrial transmural pressure and right atrial transmural pressure and cardiac output was significantly different. Conclusions The change of cardiac function caused by the increase of abdominal pressure in laparoscopic surgery is a complicated process not only related to the size of pneumoperitoneum but also related to the hemodynamic status of the body