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目的观察前列地尔治疗急性脑梗死的疗效及安全性。方法86例急性脑梗死患者,分为治疗组43例,对照组43例。治疗组给予前列地尔10μg加生理盐水100ml,ivgtt,qd,对照组常规给予曲克芦丁0.4g加生理盐水250ml,ivgtt,qd,另口服阿司匹林75mg/d,每组疗程均2周。结果治疗组痊愈18例,总有效率93.0%,对照组痊愈10例,总有效率23.3%,治疗组明显优于对照组。结论前列地尔是治疗脑梗死安全有效的药物。
Objective To observe the efficacy and safety of alprostadil in the treatment of acute cerebral infarction. Methods A total of 86 patients with acute cerebral infarction were divided into treatment group (43 cases) and control group (43 cases). The treatment group was given alprostadil 10μg plus saline 100ml, ivgtt, qd, the control group given conventional troxerutin 0.4g plus saline 250ml, ivgtt, qd, and the other oral aspirin 75mg / d, each course of treatment were 2 weeks. Results The treatment group cured 18 cases, the total effective rate 93.0%, the control group recovered 10 cases, the total effective rate was 23.3%, the treatment group was significantly better than the control group. Conclusion Alprostadil is a safe and effective drug for the treatment of cerebral infarction.