论文部分内容阅读
目的评价持续气道正压通气治疗对2型糖尿病(T2DM)合并阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者血糖及生活质量的影响。方法选择2014年1-12月我院收治的2型糖尿病合并OSAHS患者60例,随机分为干预组和对照组。对照组给予2型糖尿病的常规治疗及OSAHS的一般治疗,干预组患者在此基础上同时使用持续气道正压通气呼吸机治疗。比较两组治疗前后呼吸暂停低通气指数(AHI)、最低血氧饱和度(LSpO2)、空腹血糖(FPG)、餐后2h血糖(PPG)、糖化血红蛋白(HbA1c)及Calgary生活质量指数(SAQLI)。结果3个月后,干预组AHI、LSpO2及SAQLI总分较对照组高,FPG、PPG及HbA1c较对照组低,差异均有统计学意义(P<0.05)。结论持续气道正压通气治疗T2DM合并OSAHS患者可以改善睡眠呼吸情况,有效降低血糖,提高生活质量。
Objective To evaluate the effect of continuous positive airway pressure on blood glucose and quality of life in patients with type 2 diabetes mellitus (T2DM) complicated with obstructive sleep apnea-hypopnea syndrome (OSAHS). Methods Sixty patients with type 2 diabetes mellitus and OSAHS admitted from January to December 2014 in our hospital were randomly divided into intervention group and control group. The control group was given conventional treatment of type 2 diabetes mellitus and general treatment of OSAHS. Patients in the intervention group were treated with continuous positive airway pressure ventilator on the basis of this. The AHI, LSpO2, FPG, PPG, SAQI and HbA1c were compared between the two groups before and after treatment. . Results After 3 months, the total scores of AHI, LSpO2 and SAQLI in the intervention group were higher than those in the control group. The levels of FPG, PPG and HbA1c in the intervention group were lower than those in the control group (P <0.05). Conclusion Continuous positive airway pressure therapy for T2DM patients with OSAHS can improve sleep breathing, reduce blood sugar and improve quality of life.