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将88例心室晚电位(VLP)阳性的室性心律失常(VA)患者随机分为A、B两组,分别服倍他乐克及莫雷西嗪,四周后复查24小时动态心电图(DCG)及VLP。结果表明:莫雷西嗪虽能有效控制VA(33/42),但不能使VLP转阴,且有促心律失常作用(3/42),而倍他乐克不但能较好控制VA(38/46),且可使阳性的VLP逆转(39/46),又无促心律失常及其它明显副作用。后者用量为50~100mg/d时剂量与疗效之间无明显关系。作者认为,对VLP阳性的VA考虑药物治疗时,只要无应用β-受体阻滞剂的禁忌证,可首选倍他乐克。
Eighty-eight patients with ventricular late-ventricular (VLP) -positive ventricular arrhythmias (VA) were randomly divided into A and B groups and received metoprolol and meticillin respectively. After 24 weeks, 24-hour ambulatory electrocardiogram (DCG) And VLP. The results showed that, although effective in controlling VA (33/42), methicillin failed to turn negative VLP and had arrhythmogenic effect (3/42), and metoprolol not only controlled VA (38 / 46) and reversed the positive VLP (39/46) without proarrhythmic and other significant side effects. The latter dose of 50 ~ 100mg / d no significant relationship between dose and efficacy. The author believes that for the VLP-positive VA consider drug treatment, as long as there is no contraindication for β-blockers, the preferred choice of metoclei.