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在抢救急性有机磷农药中毒的综合措施中,能否正确地使用抗胆硷药物是决定抢救成败的重要因素。本文就如何合理应用抗胆硷药物谈几点体会。一、要联合用药,并有所侧重: 由于各种抗胆碱药物的作用部位、强弱是不同的,至今还没有全面对抗毒蕈样症状、烟碱样症状及中枢神经系统症状的药物,因此抢救中要联合用药,并根据临床主要症状有所侧重,才能取得满意疗效。 (一)周围作用较强的抗胆硷药:以阿托品为典型代表,另外还有山莨菪硷和樟柳硷等。因阿托品与M胆硷受体结合,可阻断乙酰胆硷和M胆硷受体结合,且以阻断外源性乙酰胆硷作用最强,因此阿托品能有
In the rescue of acute organophosphorus pesticide poisoning comprehensive measures, the correct use of anti-cholinergic drugs is an important factor in determining the success or failure of the rescue. This article on how to rational use of anti-cholinergic drugs to talk about some experience. First, to be combined with medication, and have focused: Because of the role of anticholinergic drugs site, the strength is different, so far there is no comprehensive fight against poisonous mushroom-like symptoms, nicotinic-like symptoms and central nervous system symptoms of drugs, so the rescue To the combination of medication, and according to the main clinical symptoms have focused, in order to obtain satisfactory results. (A) around the role of strong anti-cholinergic drugs: Atropine for the typical representatives, in addition to anisodamine and anisodine and so on. Because atropine and M choline receptor binding, can block the acetylcholine and M choline receptor binding, and to block the most exogenous acetylcholine effect, so the atropine can have