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目的探讨地西泮加芬太尼联合清醒镇静/镇痛法在早期人工流产中应用的可行性及有效性。方法选择自愿行人工流产、无流产禁忌症正常早孕妇女400例分试验组和对照组,试验组术中静脉应用芬太尼及地西泮,术前肌内注射阿托品,对照组未采用任何药物,比较两组患者对疼痛的反应、宫颈扩张度、及人流综合症及术中出血量。结果试验组镇痛效果、宫口松弛度明显高于对照组。差异有显著性(p<0.01)。人流综合症试验组明显低于对照组,两组中出血量差异无显著性(p>0.05)。结论芬太尼、地西泮联合阿托品用于人工流产术中镇痛效果显著可靠,操作方便,价格低廉,易于被普通患者接受,是安全可靠方便的减痛人工流产法。
Objective To investigate the feasibility and effectiveness of diazepam plus fentanyl combined with conscious sedation / analgesia in early induced abortion. Methods 400 cases of normal early pregnant women with contraindications of abortion were randomly divided into experimental group and control group. Intravenous fentanyl and diazepam were used in the experimental group, intramuscular injection of atropine was given before operation, and no drug was used in the control group The pain response, cervical dilatation, flow-induced syndrome and intraoperative blood loss were compared between the two groups. Results The experimental group analgesic effect, cervix laxity was significantly higher than the control group. The difference was significant (p <0.01). The experimental group was significantly lower than the control group, no significant difference in bleeding between the two groups (p> 0.05). Conclusion Fentanyl, diazepam combined with atropine for abortion in the analgesic effect was significant and reliable, easy to operate, inexpensive, easy to be accepted by ordinary patients, is safe and reliable pain relief induced abortion method.