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目的通过对老年糖尿病患者与正常人心率减速力和心率变异性的分析,探讨心率减速力的检测对于预测老年糖尿病患者心血管事件的发生变化规律。方法选取正常组:50岁~70岁无糖尿病患者100例,糖尿病组:50岁~70岁有糖尿病但未发生心血管事件者100例,全部做24h动态心电图监测,采集心率减速力(DC)、心率加速力(AC)、心率变异的低频(LF)、高频(HF)、总体标准差(SDNN)、静息心率(RHR)、平均心率(AHR)、夜间心率(NHR)进行统计分析。结果糖尿病组与正常组比:DC、AC、LF、HF、SDNN的均值均显著减低。结论糖尿病患者随着心脏自主神经功能下降,心率逐渐减低,心血管事件的发生较非糖尿病患者机率增高。
Objective To analyze the changes of heart rate deceleration and heart rate variability in elderly patients with diabetes mellitus and normal subjects to explore the changes of heart rate deceleration in predicting cardiovascular events in elderly patients with diabetes mellitus. Methods One hundred normal subjects were enrolled in this study. One hundred patients aged 50-70 years with no diabetes mellitus, 100 patients with diabetes mellitus aged 50 years to 70 years with diabetes who did not have cardiovascular events were enrolled in this study. All patients were monitored for 24h ambulatory electrocardiogram (ECG) , Heart rate acceleration (AC), heart rate variability (LF), high frequency (HF), total standard deviation (SDNN), resting heart rate (RHR), mean heart rate (AHR), nocturnal heart rate (NHR) . Results Compared with normal group, the mean of DC, AC, LF, HF, SDNN in diabetic group was significantly decreased. Conclusions With the decrease of cardiac autonomic function and heart rate in diabetic patients, the incidence of cardiovascular events is higher than that of non-diabetic patients.