生殖器官肿瘤的流行病学资料分析表明,性混乱是一个公认的危险因素。患有宫颈癌妇女或患有阴茎癌男子的性配偶中,也发现生殖器官癌有较高的比率。这表明至少有一个传染性因子在宫颈癌病因中起了重要的作用。许多实验资料证明,病毒可能是首要的致癌因子。早在60年代,Nahmias等首先报道了单纯疱疹病毒Ⅱ型(HSV-2)与宫颈癌的关系,并且提出,HSV-2可能是宫颈癌的潜在致癌因子。而后,许多学者致力于这方面的研究,获得了许多宝贵资料。 Epidemiological data analysis of genital tumors shows that sexual confusion is a recognized risk factor. A higher rate of genital cancer was also found in women with cervical cancer or in males with penile cancer. This shows that at least one infectious agent plays an important role in the etiology of cervical cancer. Many experimental data show that the virus may be the primary carcinogen. As early as the 1960s, Nahmias et al. First reported the relationship between herpes simplex virus type 2 (HSV-2) and cervical cancer and proposed that HSV-2 may be a potential carcinogen for cervical cancer. Afterwards, many scholars devoted themselves to this research and got a lot of valuable information.