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目的：探讨精神分裂症后抑郁患者认知心理治疗的临床效果。方法将74例精神分裂症后抑郁患者随机分为两组，均予以抗精神病药物治疗，研究组在此基础上联合认知心理治疗，观察12周。于治疗前和治疗各时段采用简明精神病量表、汉密顿抑郁量表评定临床疗效。结果治疗后两组简明精神病量表、汉密顿抑郁量表评分均较治疗前显著降低（ P ＜0．01），研究组较对照组下降更显著（P ＜0．01）；研究组总有效率为97．3％。对照组为64．9％，研究组显著高于对照组（P＜0．01）。结论认知心理治疗能有效改善精神分裂症后抑郁患者的抑郁症状，显著提高临床疗效。“,”Objective To explore the clinical effect of cognitive psychotherapy (CPT ) for post‐schizo‐phrenic depression (PSD) .Methods Seventy‐four PSD patients were randomly assigned to two groups , both groups received antipsychotic treatment ,and on thid basis research group was plus CPT for 12 weeks .Clinical effects were assessed with the Brief Psychiatric Rating Scale (BPRS) and Hamilton De‐pression Scale (HAMD) before and after treatment .Results The BPRS and HAMD scores of both groups lowered more significantly after treatment compared with pretreatment (P< 0 .01) ,so did those in re‐search than control group (P<0 .01);total effective rate was significantly higher in research than control group (97 .3% vs .64 .9% ,P<0 .01) .Conclusion CPT could effectively improve depressive symptoms of PSD patients and raise clinical effect .