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目的了解肠切除肠吻合术新生儿术中输血现状、术中输血的影响因素及其对预后的影响。方法回顾性分析2010~2013年间于重庆医科大学附属儿童医院行剖腹探查、肠切除肠吻合术新生儿病历资料185例,按照是否有术中输血,分为输血组和非输血组。可疑的影响因素进行组间比较后,将差异有统计学意义的因素进行多因素logistic回归分析,筛选新生儿术中输血的影响因素;并分析不同贫血严重程度新生儿术中输血对预后的影响。结果术中输注悬浮红细胞96例,输注率为51.89%。logistic回归分析显示,术前Hb浓度、术中出血量、手术时间是新生儿术中输血的影响因素。中度贫血、轻度贫血、非贫血新生儿术中输血未能明显改善预后。结论术前Hb浓度、术中出血量、手术时间是新生儿术中输血的独立影响因素;术中轻度、中度贫血对新生儿预后无明显影响,可不予输血治疗。
Objective To understand the status of blood transfusion in neonates undergoing intestinal resection of intestinal anastomosis, influencing factors of intraoperative blood transfusion and its effect on prognosis. Methods Retrospective analysis of 185 cases of neonate neonates with laparotomy and enteral resection of intestinal anastomosis at Children’s Hospital of Chongqing Medical University from 2010 to 2013 was performed and divided into transfusion group and non-transfusion group according to whether there was intraoperative blood transfusion. Susceptible factors were compared between groups, the differences were statistically significant factors multivariate logistic regression analysis of screening neonatal intraoperative blood transfusion factors; and analysis of different anemia severity neonatal intraoperative blood transfusion prognosis . Results 96 cases of intraoperative infusions of red blood cells, the infusion rate was 51.89%. Logistic regression analysis showed that preoperative Hb concentration, intraoperative blood loss, operation time is the influencing factor of neonatal intraoperative blood transfusion. Blood transfusion in moderate anemia, mild anemia and non-anemic neonates failed to significantly improve the prognosis. Conclusions The preoperative Hb concentration, intraoperative blood loss and operation time are the independent influencing factors of neonatal intraoperative blood transfusion. Mild and moderate anemia during operation have no obvious effect on the prognosis of newborns, and may not be transfused.