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目的:探讨孕妇缺铁时新生儿的影响。方法:对187例孕妇血液和产时脐血的5项铁参数进行跟踪,其中77例分为补铁组和对照组。结果:(1)孕妇缺铁率随着孕周的增加而增加,临产时为97.73%;(2)孕妇缺铁越早,其脐血Hb、血清铁(SI)、转铁蛋白饱和度(TS)、血清铁蛋白(SF)越低,总铁结合力(TIBC)越高,孕20~26周与临产比较SI和SF差异均有显著意义(P<0.05和P<0.01),脐血SI和SF与母血SF正相关(r=0.31,P<0.01和r=0.18,P<0.05);(3)补铁组脐血的Hb,SI,TS,SF比对照组高,TIBC比对照组低,两组SI和SF比较,差异有显著意义(P<0.05和P<0.01)。结论:孕妇缺铁性贫血发生率高,新生儿铁贮备降低,必须进行补铁治疗。
Objective: To explore the impact of newborns in pregnant women with iron deficiency. Methods: Five iron parameters of 187 pregnant women with blood and umbilical cord blood were tracked, of which 77 were divided into iron supplementation group and control group. Results: (1) The rate of iron deficiency in pregnant women increased with the increase of gestational age and reached 97.73% during labor; (2) The earlier iron deficiency in pregnant women, the serum Hb, serum iron (SI) and transferrin saturation (TS) and serum ferritin (SF), the higher the total iron binding capacity (TIBC), the difference between SI and SF at 20 ~ 26 weeks gestation was significant (P <0.05 and P <0 .01). Serum SF and SF were positively correlated with SF in umbilical cord blood (r = 0.31, P <0.01 and r = 0.18, P <0.05) Hb, SI, TS, SF were higher than the control group, and TIBC was lower than the control group. There was significant difference between the two groups in SI and SF (P <0.05 and P <0.01). Conclusion: The incidence of iron deficiency anemia in pregnant women is high, and neonatal iron stores are reduced. Iron supplementation is necessary.