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目的:探讨角膜内皮细胞在粘性小管切开术或小梁切除术后的变化及临床意义。方法:采用非接触眼压计,角膜内皮计及细胞图像分析系统观察16例粘性小管切开术,25例小梁切除术手术前后眼压、中央角膜厚度、角膜内皮细胞情况,并对结果进行统计学分析。结果:粘性小管切开术组术后眼压显著下降(P<0.05),中央角膜厚度(CCT),最小细胞面积(MIN),最大细胞面积(MAX),平均细胞面积(AVE),细胞面积变异系数(CV),细胞密度(CD)均较术前无显著性差异(P>0.05)。小梁切除组术后眼压显著下降(P<0.05),中央角膜厚度(CCT)较术前增加(P<0.05),平均细胞面积(AVE)较术前增加(P<0.05),细胞密度(CD)及六角形细胞百分数(H%)均较术前显著减少(P<0.05)。结论:粘性小管切开术和小梁切除术均可有效控制眼压,粘性小管切开术后角膜内皮细胞变化较小,手术安全性高。
Objective: To investigate the changes and clinical significance of corneal endothelium after viscous tubuleotomy or trabeculectomy. Methods: Non-contact tonometer, corneal endothelium and cell image analysis system were used to observe the changes of intraocular pressure, central corneal thickness and corneal endothelial cells in 16 cases of viscous tubule incision, 25 cases of trabeculectomy, and the results were performed Statistical analysis. Results: The intraocular pressure (IOP) decreased significantly (P <0.05), the central corneal thickness (CCT), the minimum cell area (MIN), the maximum cell area (AVE), the cell area There were no significant differences in CV and CD between the two groups (P> 0.05). The intraocular pressure of trabeculectomy group decreased significantly (P <0.05), the central corneal thickness (CCT) increased (P <0.05), the mean cell area (AVE) increased (P <0.05) (CD) and hexagonal cells (H%) were significantly decreased compared with preoperative (P <0.05). CONCLUSION: Viscoelastic tube trabeculectomy and trabeculectomy can both control the intraocular pressure effectively. The change of corneal endothelial cells after the adhesive tube incision is small, and the operation safety is high.