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目的 分析2005-2017年贵州省国家免疫规划 (NIP) 针对传染病学校突发公共卫生事件 (Public health emergencyevent, PHEE) 流行病学特征.方法 通过中国PHEE报告信息系统收集贵州省2005-2017年NIP针对传染病学校PHEE数据, 进行描述流行病学分析.结果2005-2017年贵州省共报告NIP针对传染病学校PHEE 433起, 报告病例14 236例, 总罹患率为1.8%.各年报告PHEE在3起 (2005年)-92起 (2008年) 之间.麻疹、风疹、流行性腮腺炎、甲型肝炎、流行性脑脊髓膜炎、乙型脑炎PHEE分别占1.2%、15.7%、75.5%、5.3%、0.5%、1.8%, 病例数 (罹患率) 分别为125例 (0.2%) 、1 889例 (3.1%) 、10 454例 (3.6%) 、1 742例 (0.8%) 、13例 (0.6%) 、13例 (0.01%) .幼儿园、小学、初中、工读学校、高等院校PHEE数分别占2.3%、93.3%、0.7%、3.2%、0.5%, 病例数 (罹患率) 分别为211例 (0.3%) 、12 732例 (1.9%) 、59例 (1.7%) 、673例 (4.5%) 、561例 (2.4%) .农村、城镇地区PHEE数分别占82.4%和17.6%.结论2005-2017年贵州省NIP针对传染病学校PHEE呈下降趋势.需重点加强农村地区学校的接种查验和NIP疫苗接种工作.“,”Objective To analyze characteristics of school-based public health emergency events (PHEEs) of National Immunization Program (NIP) targeted diseases in Guizhou province during 2005-2017. Methods We used the National PHEE Reporting System to obtain data on school-based PHEEs of NIP-targeted diseases during 2005-2017 in Guizhou for a descriptive epidemiological analysis. Results A total of 433 school-based PHEEs of NIP-targeted diseases were reported in Guizhou during 2005-2017, comprising 14 236 reported cases, for an attack rate of 1.8%. The number of reported PHEEs ranged f rom 3 (2005) to 92 (2008) by year. Measles, rubella, mumps, hepatitis A, meningococcal meningitis, and Japanese encephalitis PHEEs accounted for 1.2%, 15.7%, 75.5%, 5.3%, 0.5%, and 1.8%, respectively, with the numbers of cases (attack rates) of 125 (0.2%), 1 889 (3.1%), 10 454 (3.6%), 1 742 (0.8%), 13 (0.6%), and 13 (0.01%). PHEEs in kindergartens, primary schools, middle schools, ref orm schools, and universities accounted f or2.3%, 93.3%, 0.7%, 3.2%, and 0.5%, respectively, with the numbers of cases (attack rates) of 211 (0.3%), 12 732 (1.9%), 59 (1.7%), 673 (4.5%), and 561 (2.4%). PHEEs in rural and urban areas accounted for 82.4% and 17.6%. Conclusion School-based PHEEs of NIP-targeted diseases showed a decreasing trend in Guizhou during 2005-2017. We need to strengthen vaccination record checks and catch-up vaccination in rural schools.