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在西安市三所医院进行了小于胎龄儿(SGA)的病例对照研究(1:1,155对)。与SGA出生有关的产科因素为:妊高征、脐绕颈、羊水过少、胎盘形态异常、孕期用药、孕期其它疾病、妊娠间隔半年及SGA分娩史。经多元条件logistic分析表明:妊高征(中、重度)、羊水过少、脐绕颈及既往SGA分娩史4项因素被选入。SGA婴儿先天性畸形、新生儿窒息、围产期患病及围产儿死亡均高于适于胎龄儿(AGA)组,分别为AGA的9.49、4.78、5.28和8.28倍。提出了SGA的产科预防措施。
A case-control study of small gestational age (SGA) was performed in three hospitals in Xi’an (1: 1, 155 pairs). The obstetric factors associated with SGA birth are: pregnancy-induced hypertension, umbilical cord neck, oligohydramnios, placental abnormalities, medication during pregnancy, other illnesses during pregnancy, six-month gestation and SGA delivery history. Multivariate logistic analysis showed that PIH (moderate and severe), oligohydramnios, navel around the neck and previous history of SGA delivery were selected. SGA congenital malformations, neonatal asphyxia, perinatal morbidity and perinatal mortality were higher than those for gestational age (AGA) group, AGA were 9.49,4.78,5.28 and 8.28 times. Proposed SGA obstetric preventive measures.