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目的探讨注意缺陷多动障碍(attention-deficit/hyperactivity disorder,ADHD)患者一级亲属的注意功能特点。方法将80例ADHD患者一级亲属(first degree relative,FDR)及与其人口学资料相匹配的80例健康对照(healthy controls,HC)组采用连线测试、Stroop色词测试,GO/Nogo任务进行注意功能测定。结果 FDR组在连线测试-B反应时、GO/No-go任务反应时与错误数,Stroop-C反应时[分别为(89.98±23.77)s,(1172.41±427.16)ms,(2.25±2.05)次,(1114.15±463.02)ms]差于HC组[分别为(983.50±13.51)s,(834.66±306.52)ms,(1.63±1.47)次,(1006.51±338.92)ms],差异有统计学意义(分别t=2.118,P=0.018;t=5.752,P<0.001;t=2.214,P=0.014;t=1.678,P=0.048)。结论 ADHD患者一级亲属有不同程度的注意功能损害。
Objective To investigate the attentional features of first-degree relatives in patients with attention-deficit / hyperactivity disorder (ADHD). Methods Eighty first degree relatives (FDRs) of ADHD patients and 80 healthy controls (HCs) matched with their demographic data were tested by using connection test, Stroop color word test and GO / Nogo task Pay attention to function test. Results In the FDR group, there was no significant difference between the GO / No-go task response time and the number of errors in the FDR group [(89.98 ± 23.77) s, (1172.41 ± 427.16) ms, (2.25 ± 2.05) ), (1114.15 ± 463.02) ms] were worse than those in HC group [(983.50 ± 13.51) s, (834.66 ± 306.52) ms, (1.63 ± 1.47), (1006.51 ± 338.92) ms] Significance (t = 2.118, P = 0.018; t = 5.752, P <0.001; t = 2.214, P = 0.014; t = 1.678, P = 0.048). Conclusion First-degree relatives of ADHD patients have different degrees of attention impairment.