近年来,由于痢疾杆菌耐药菌株广泛存在,造成了多种抗痢疾药物敏感性下降,给临床医生带来不少困难。我院近年对住院的5例急性顽固性菌痢试用利福平治疗,获得满意效果,现报告如下。 5例病人年龄在9个月至56岁;就诊时间分别在发病后3小时～7天,均有较典型的临床症状;如发热、腹痛、腹泻、解脓血粘液大便及不同程度的里急后重、实验室检查;大便可见脓细胞、红细胞、白细 In recent years, due to the existence of drug-resistant strains of Shigella dysenteriae, the sensitivity of many anti-dysentery drugs has dropped, posing many difficulties for clinicians. In our hospital in recent years, hospitalized 5 cases of acute refractory bacillary dysentery trial of rifampicin, obtained satisfactory results, are as follows. 5 patients aged 9 months to 56 years of age; treatment time were 3 to 7 days after onset, have more typical clinical symptoms; such as fever, abdominal pain, diarrhea, pus and blood mucus stool and varying degrees of tenesmus, Laboratory tests; stool can be seen pus, red blood cells, white