恶性肿瘤是严重危害人类健康的常见疾病,早期癌症患者无明显症状及缺乏特异、敏感的诊断指标,因此传统的诊断方法难以及早发现癌症。近年来,随着分子生物学技术的发展,恶性肿瘤的早期诊断有了长足进步,特别是在基因标志方面。本文就基因标志在恶性肿瘤的研究进展方面做一综述。 Malignancy is a common disease that seriously endangers human health. Early cancer patients have no obvious symptoms and no specific and sensitive diagnostic indicators. Therefore, it is difficult to detect cancer early by traditional diagnostic methods. In recent years, with the development of molecular biology techniques, there have been considerable advances in the early diagnosis of malignant tumors, especially in the area of ​​genetic markers. This article reviews the progress of genetic markers in malignant tumors.