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由于放射治疗癌瘤患者越趋成功,以及育龄的放疗患者关心未来小孩的危险度,对认清射线照射是否增加人类配子染色体异常的风险显得更加重要。因可用的人类卵子没有足够的数量,加之在受精后到雄原核形成才能见到人类精子染色体,以及不可能借助直接的染色体分析来研究人类的配子等原因,因此阻碍了这项工作的开展。作者选用放疗的癌瘤患者共13例,年龄为19～47岁。其中8例以前生过一个小孩,5例尚无小孩。患者的癌瘤类型、总的辐射剂量和睾丸辐射剂
As radiotherapy cancer patients become more successful and patients of childbearing age care about the risk of future children, it is even more important to recognize that exposure to radiation increases the risk of chromosomal abnormalities in human gametes. This is hampered by the fact that not enough numbers of available human eggs are available, together with human sperm chromosomes after fertilization to form male pronuclei, and it is not possible to study human gametes with direct chromosomal analysis. The authors selected a total of 13 cases of cancer patients with radiotherapy, aged 19 to 47 years. Of these, eight had one child before, and five did not yet have a child. The patient’s type of cancer, the total radiation dose, and testis radiation