论文部分内容阅读
评价有不明原因妊娠早期习惯性流产史的孕妇,妊娠期预防血栓形成治疗的有效性。方法:研究对象为两组:组A为已知原因的习惯性流产史孕妇(n=24);组B为不明原因的习惯性流产史孕妇(n=27)。自探及胎心开始,给予小剂量阿司匹林和低分子量肝素(LMWH),持续至孕37周。结果:两组治疗成功率(妊娠存活时间>24周)均较高,效果相当,分别为组A83.3%及组B85.1%。组A报告的并发症(先兆子痫、IUGR、胎盘早剥、注射部位血肿及皮肤反应)稍多,但两组间无显著性差异。阴道分娩及剖宫产过程中无异常出血。结论:研究结果再次肯定了先前的报道:孕期LMWH与小剂量阿司匹林联合应用安全有效。对已知及未知原因的习惯性流产史孕妇,治疗同样有效。
Evaluation of unexplained pregnant women with a history of first trimester of pregnancy, the effectiveness of thrombosis prevention during pregnancy. METHODS: The subjects were two groups: group A, a known history of pregnant women with habitual abortion (n = 24); group B, unidentified women with habitual abortion (n = 27). Since exploration and fetal heart rate, low-dose aspirin and low-molecular-weight heparin (LMWH) have been administered for 37 weeks. Results: The success rate of treatment (pregnancy survival time> 24 weeks) was higher in both groups, with the same effect, which was 83.3% in group A and 85.1% in group B, respectively. Group A reported slightly more complications (preeclampsia, IUGR, placental abruption, injection site hematoma, and skin reactions), but there was no significant difference between the two groups. Vaginal delivery and cesarean section without abnormal bleeding. CONCLUSIONS: The findings reaffirmed previous reports that LMWH during pregnancy is safe and effective in combination with low-dose aspirin. The same applies to pregnant women with a history of habitual abortion of known and unknown causes.