本文报道了金属锡粉促进下含氮芳杂环的烯丙基化反应.在氯甲酸酯存在下,利用烯丙基溴和金属锡原位生成的烯丙基锡试剂作为亲核试剂捕捉体系中的N-酰化季铵盐,合成了一系列烯丙基取代N-酰基杂环衍生物.反应对于咪唑,噻唑,吡啶,嘧啶等含氮含硫的杂环都适用,并且对于巴豆基溴的反应表现出良好的区域选择性. In this paper, we reported the allylation reaction of nitrogen-containing aromatic heterocycles with metal tin powder.Using allyl bromide generated in situ with allyl bromide and metal tin as the nucleophile in the presence of chloroformate System of N-acylated quaternary ammonium salts, a series of allyl substituted N-acyl heterocyclic derivatives were synthesized.The reaction is suitable for nitrogenous sulfur containing heterocycles such as imidazole, thiazole, pyridine, pyrimidine and so on, The reaction of bromine shows good regioselectivity.