论文部分内容阅读
德国科学家最近阐明了一个细菌回收m RNA上停滞核糖体的新机制,当m RNA上缺少终止密码子就会导致核糖体无法从m RNA上脱离。参与该过程的蛋白为未来开发新抗生素药物提供了潜在靶点。对传统抗生素产生抵抗的抗药细菌越来越成为一个严重的医学难题,因此急需开发可以攻击新靶点的新抗生素。许多抗生素通过作用于细
Recently, German scientists have elucidated a new mechanism for bacteria to recover stagnant ribosomes on m RNAs. The lack of a stop codon on m RNA results in the failure of ribosomes to detach from m RNAs. The proteins involved in this process provide potential targets for the development of new antibiotics in the future. Drug-resistant bacteria that resist traditional antibiotics are increasingly becoming a serious medical problem and there is an urgent need to develop new antibiotics that can attack new targets. Many antibiotics act on fine