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目的观察老年晚期胃肠道肿瘤采用姑息治疗对其生活质量的影响。方法选取医院收治的晚期胃肠道肿瘤老年患者58例,随机分为对照组和观察组,每组29例。观察组采用常规FOLFOX6化疗方案治疗;观察组在此基础上,采用姑息治疗。观察2组治疗后生命质量核心量表(QLQ-C30)评分。结果与对照组比较,观察组的情绪功能、角色功能、认知功能、恶心呕吐、疲乏、疼痛、便秘、失眠、厌食及总体健康状况评分均较优良(P<0.01或P<0.05)。结论老年晚期胃肠道肿瘤患者应用姑息治疗更能有效提高治疗效果,改善生活质量,值得临床推广应用。
Objective To observe the effects of palliative treatment on the quality of life of elderly patients with advanced gastrointestinal cancer. Methods Fifty-five elderly patients with advanced gastrointestinal cancer who were admitted to hospital were randomly divided into control group and observation group, with 29 cases in each group. The observation group was treated with routine FOLFOX6 chemotherapy; on the basis of this observation group, palliative treatment was used. The QLQ-C30 scores of two groups were observed after treatment. Results Compared with the control group, the observation group had better scores of emotional function, role and function, cognitive function, nausea and vomiting, fatigue, pain, constipation, insomnia, anorexia and general health status (P <0.01 or P <0.05). Conclusion The application of palliative treatment in elderly patients with advanced gastrointestinal cancer can effectively improve the therapeutic effect and improve the quality of life, which is worthy of clinical application.