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目的探讨依达拉奉与氯吡格雷联合治疗急性脑梗死的临床疗效。方法选取我院2013年5月至2016年5月收治的116例急性脑梗死患者为研究对象,根据随机数字表法分为研究组和对照组,其中对照组58例患者给予依达拉奉进行治疗,研究组58例患者在对照组的基础上联合使用氯吡格雷进行治疗,对比两组的临床治疗效果、神经功能缺损评分及治疗前后患者血液流变学指标水平。结果研究组治疗总有效率显著高于对照组,差异有统计学意义(P<0.05),治疗后60天两组的神经功能缺损评分及血液流变学指标水平均呈下降趋势(P<0.05),且研究组明显优于对照组(P<0.05)。结论对急性脑梗死患者采用氯吡格雷联合依达拉奉联合治疗,能有效提高临床疗效,降低神经功能缺损评分,值得临床推广。
Objective To investigate the clinical efficacy of edaravone and clopidogrel in the treatment of acute cerebral infarction. Methods One hundred and sixty-six patients with acute cerebral infarction admitted to our hospital from May 2013 to May 2016 were selected as the study group and the control group according to the random number table. 58 patients in the control group were treated with edaravone Treatment, study group of 58 patients in the control group based on the combination of clopidogrel for treatment, compared the two groups of clinical treatment, neurological deficit score and the level of hemorheology in patients before and after treatment. Results The total effective rate of the study group was significantly higher than that of the control group (P <0.05). After 60 days of treatment, the neurological deficit scores and hemorheological indexes of the two groups showed a decreasing trend (P <0.05 ), And the research group was significantly better than the control group (P <0.05). Conclusion Clopidogrel combined with edaravone in patients with acute cerebral infarction can effectively improve the clinical efficacy and reduce the score of neurological deficit, which deserves clinical promotion.