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目的:调查湖北地区性滥人群庚型肝炎病毒(HGV)感染状况。方法:检查309例有性滥史者的血清HGV感染标志物,用ELISA方法检测抗HGV。结果:309例性滥者HGV的感染率11.97%(37例),显著高于普通人群(1.51%,19/1257例)。女性HGV的感染率(12.36%,32/259例)与男性HGV的感染率(10%,5/50例)无显著差异。性滥时间大于2年者抗HGV阳性率17.05%(30/176例)显著高于性滥时间小于2年者5.26%(7/133例)。女性中有吸毒史者的HGV感染率(22.37%,17/76例)显著高于未吸毒者(8.20%,15/183例)。所有HGV感染者的肝功能正常。结论:性滥人群具有较高的HGV感染率,HGV可能通过性途径传播。性滥人群HGV的感染率与性滥时间呈正相关,吸毒增加了性滥者HGV感染的风险。
Objective: To investigate the prevalence of hepatitis G virus (HGV) in Hubei area. Methods: The serum HGV markers in 309 cases of sexual abusers were examined, and anti-HGV was detected by ELISA. Results: The prevalence of HGV among 309 aggressive patients was 11.97% (37 cases), which was significantly higher than that of the general population (1.51%, 19/1257 cases). The prevalence of HGV among women (12.36%, 32/259 cases) was not significantly different from that of male HGV (10%, 5/50). The anti-HGV positive rate of 17.05% (30/176 cases) with sexual abuse time greater than 2 years was significantly higher than 5.26% (7/133 cases) of sexual abuse less than 2 years. The prevalence of HGV infection (22.37%, 17/76 cases) among women who had history of drug addiction was significantly higher than that of non-drug addicts (8.20%, 15 of 183 cases). All HGV infected people had normal liver function. CONCLUSIONS: Sex abusers have a high prevalence of HGV infection and HGV may be transmitted by sexual route. The prevalence of HGV among sex abusers is positively correlated with the frequency of sexual abuse, and drug addiction increases the risk of HGV infection among sexually abused persons.