论文部分内容阅读
目的 :观察平阳霉素治疗血管瘤、血管畸形后引起的组织学变化。方法 :13例不同类型的血管病变 ,分1～ 3次注射平阳霉素 4～ 2 4mg ,多次注射者间隔 10～ 12d .在末次注射后 12～ 15d切除治疗后的病变组织进行组织学观察。结果 :注射 1次的标本中血管壁增厚 ,管腔变狭窄 ;注射 2次的标本中管腔闭塞 ,管壁失去正常结构 ;注射 3次的标本中管壁结构消失 ,组织纤维化。结论 :平阳霉素瘤腔内注射后可引起血管内膜变化 ,致使管腔闭塞 ,从而治愈血管瘤及血管畸形
Objective : To observe the histological changes caused by hemangioma treated by pingyangmycin. METHODS: Thirteen different types of vascular lesions were divided into 1 to 3 injections of Pingyangmycin 4 to 24 mg. Multiple injections were performed at intervals of 10 to 12 days. Histological observation of the lesions was performed after 12 to 15 days after the last injection. . RESULTS: Vascular thickening and luminal stenosis were found in the specimens injected once. The occlusion of the lumens in the specimens injected twice resulted in the loss of normal structure. The wall structure of the specimens disappeared after 3 injections and fibrosis. Conclusion : Intraluminal injection of bleomycin can cause changes in the vascular intima, resulting in occlusion of the lumen, thereby curing hemangiomas and vascular malformations