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目的：应用９９ｍＴｃ－甲氧基异丁基异腈（ＭＩＢＩ）心肌断层显像计算左室腔与心肌放射性计数（Ｃ／Ｍ）比值，并与平衡法核素心室显像获得的左室射血分数（ＬＶＥＦ）对照．旨在探讨该法的可靠性和临床价值。方法：受试者共２２０例，１０２例行９９ｍＴｃ－ＭＩＢＩ运动态心肌断层和静息态心室显像，１１８例接受静息态心肌断层和静息态心室显像。１周内完成２项检查。每次心肌断层显像注射９９ｍＴｃ－ＭＩＢＩ７４０ＭＢｑ，采集后重建心脏短轴、水平长轴和垂直长轴的断层图像。全部病例均常规完成平衡法核素心室显像，应用半自动程序计算出ＬＶＥＦ。分别由运动态和静息态心肌断层的短轴图像计算出Ｃ／Ｍ比值，并与ＬＶＥＦ进行相关分析。结果：核素心室显像测得的ＬＶＥＦ和心肌断层显像测得的Ｃ／Ｍ比值呈显著相关，ＬＶＥＦ与运动态Ｃ／Ｍ比值相关系数ｒ为０．６９６４，与静息态Ｃ／Ｍ比值相关系数ｒ为０．６９９５。运动态Ｃ／Ｍ和静息态Ｃ／Ｍ比值对检测静息左室功能异常的灵敏度为７１．９％、６８．６％；特异性为９２．９％、９７．０％；准确度为８６．３％、８４．７％。结论：应用９９ｍＴｃ－ＭＩＢＩ心肌断层显像计算Ｃ／Ｍ比值可初步评价冠心病患者的静息左室功能状况，其重复性?
OBJECTIVE: To calculate left ventricular and myocardial radioactive count (C / M) ratio by 99mTc-methoxyisobutylisonitrile (MIBI) myocardial perfusion imaging and to compare with left ventricular ejection fraction LVEF) control. To explore the reliability and clinical value of the law. METHODS: A total of 220 subjects underwent 99mTc-MIBI motorized myocardial infarction and resting ventriculogram, and 118 patients underwent resting myocardial infarction and resting ventriculogram. 1 check completed within 1 week. 99mTc-MIBI740MBq was injected into each myocardial imaging, and the images of cardiac short axis, horizontal long axis and vertical long axis were collected and reconstructed. All cases were routinely completed equilibrium method radionuclide ventricular imaging, the application of semi-automatic procedures to calculate LVEF. The C / M ratio was calculated from the short-axis images of the motor and resting myocardial slices, respectively, and correlated with LVEF. Results: The LVEF measured by radionuclide imaging was significantly correlated with the C / M ratio measured by myocardial tomography. The correlation coefficient r between LVEF and C / M ratio was 0.6964, which was significantly different from resting C / M The ratio correlation coefficient r was 0.6995. The sensitivities of exercise C / M and resting C / M were 71.9%, 68.6%, specificity of 92.9%, 97.0%, respectively. The accuracy was 86.3%, 84.7%. Conclusion: 99mTc-MIBI myocardial perfusion imaging C / M ratio can be used to evaluate the resting left ventricular function in patients with coronary heart disease, its reproducibility?