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目的:了解我院抗HBV(乙型肝炎病毒)核苷类似物的应用情况及发展趋势,为临床合理用药提供参考。方法:根据医院网络系统,对我院抗HBV核苷类似物的用药金额、限定日剂量(DDD)、用药频度(DDDs)等分别进行统计分析。结果:我院HBV核苷类似物的应用呈现逐年增长趋势,慢性乙型肝炎抗病毒治疗正在被医生和患者所接受。结论:应规范合理使用核苷类似物,进一步优化治疗方案,降低耐药变异率。
Objective: To understand the application of anti-HBV (Hepatitis B virus) nucleoside analogues in our hospital and its development trend, so as to provide a reference for clinical rational drug use. Methods: According to the hospital network system, the amount of anti-HBV nucleoside analogues in our hospital, the daily dose limit (DDD), frequency of medication (DDDs) were statistically analyzed. Results: The application of HBV nucleoside analogues in our hospital showed an increasing trend year by year. Chronic hepatitis B antiviral therapy is being accepted by doctors and patients. Conclusion: The rational use of nucleoside analogues should be standardized to further optimize treatment options and reduce the rate of drug resistance mutation.