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Src蛋白是一类由许多细胞外信号分子激活的非受体蛋白酪氨酸激酶,广泛存在于组织细胞中,通过与信号转导通路中重要分子的相互作用,参与细胞的代谢过程,调控细胞的生长和分化过程。Src蛋白主要以两种形式存在:病毒癌基因表达蛋白v-Src和细胞癌基因表达蛋白c-Src,两者具有基因同源性。c-Src蛋白与癌细胞生长、发展关系密切。但近年来的研究发现,c-Src蛋白高度活化或过量表达可促进骨质疏松症的发生
Src protein is a class of non-receptor protein tyrosine kinases activated by many extracellular signal molecules, widely exists in the tissue cells, through the interaction with important molecules in the signal transduction pathway, participating in the metabolic process of the cells, regulating the cells The growth and differentiation process. The Src protein mainly exists in two forms: the viral oncogene v-Src and the oncogene c-Src, both of which have gene homology. c-Src protein and cancer cell growth and development are closely related. However, recent studies have found that c-Src protein activation or overexpression can promote the occurrence of osteoporosis