本文报告了放免法测定正常人和垂体-肾上腺疾病患者血清N-POMC水平。结果表明正常人和单纯肥胖者血清N-POMC空腹值分别是182.9±78.2和164.5±86.4pg/ml,两者无明显差别。同时正常人有昼夜节律改变,小剂量地塞米松抑制明显。柯兴氏病组624.4±196.2pg/ml,与前两组差别显著,且节 This article reports the serum levels of N-POMC measured by radioimmunoassay in patients with normal and pituitary-adrenal diseases. The results showed that normal people and simple obesity serum N-POMC fasting values ​​were 182.9 ± 78.2 and 164.5 ± 86.4pg / ml, no significant difference between the two. At the same time, circadian rhythm changes in normal people, low-dose dexamethasone significantly inhibited. Cushing’s disease group 624.4 ± 196.2pg / ml, significant difference with the first two groups, and section