目的:观察盐酸小檗碱联合磷酸铝凝胶灌肠治疗小儿急性肠炎的临床疗效。方法:将150例急性肠炎患儿随机分为观察组和对照组各75例,两组均予抗生素、微生态制剂及补液等治疗,观察组加用盐酸小檗碱联合磷酸铝凝胶灌肠,比较两组总有效率及临床症状改善情况。结果:治疗后观察组总有效率为93.33%,对照组总有效率为86.67%,两组比较差异有统计学意义(χ2=4.981,P<0.05);观察组腹泻缓解时间、退热时间、大便常规正常时间都明显短于对照组,差异有统计学意义(P<0.05)。结论:盐酸小檗碱联合磷酸铝凝胶灌肠治疗小儿急性肠炎疗效显著,值得临床推广应用。 Objective: To observe the clinical efficacy of berberine combined with aluminum phosphate gel enema in children with acute enteritis. Methods: 150 children with acute enteritis were randomly divided into observation group and control group, with 75 cases in each group. The two groups were treated with antibiotics, probiotics and rehydration. The observation group was treated with berberine combined with aluminum phosphate gel enema, The total effective rate and clinical symptoms were compared between the two groups. Results: After treatment, the total effective rate was 93.33% in the observation group and 86.67% in the control group, with significant difference between the two groups (χ2 = 4.981, P <0.05). The diarrhea relief time, Stool routine normal time were significantly shorter than the control group, the difference was statistically significant (P <0.05). Conclusion: Berberine combined with aluminum phosphate gel enema in children with acute colitis has significant curative effect, which is worthy of clinical application.