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目的:探究连续性血液净化治疗对于重症胰腺炎患者的临床治疗效果。方法:选择临沧市人民医院2015年1月至2015年12月收治的重症胰腺炎患者15例作为观察组,实施常规治疗联合连续性血液净化治疗。选取以往本院收治的未采用连续性血液净化治疗的重症胰腺炎患者20例作为对照组,然后观察患者治疗前后空腹血糖(FBG)、血淀粉酶(AMS)水平,同时对比观察患者的氧化应激功能各指标的变化超氧化物歧化酶(SOD)、过氧化氢酶(CAT)、丙二醛(MDA)、谷胱甘肽过氧化物酶(GSH-PX)和两组氧合指数的变化。结果:经过治疗后两组患者FBG、AMS均明显改善,且观察组改善情况明显优于对照组,两组患者治疗前各项指标(SOD、CAT、MDA及GSH-PX)比较差异均无统计学意义(P>0.05),经过治疗后,以上指标均发生明显改善,并且改善情况观察组优于对照组,且氧合指数改善优于对照组,差异具有统计学意义(P<0.05)。结论:连续性血液净化治疗用于重症胰腺炎患者的治疗,具有重要的应用价值。
Objective: To investigate the clinical effect of continuous blood purification therapy on patients with severe acute pancreatitis. Methods: Fifteen patients with severe pancreatitis admitted from January 2015 to December 2015 in Lincang People’s Hospital were selected as the observation group and received routine treatment combined with continuous blood purification. Twenty patients with severe pancreatitis who did not use continuous blood purification in our hospital were selected as the control group. The levels of fasting blood glucose (FBG) and serum amylase (AMS) before and after treatment were observed. The patients’ The changes of various indices of the activation index of superoxide dismutase (SOD), catalase (CAT), malondialdehyde (MDA), glutathione peroxidase (GSH-PX) Variety. Results: After treatment, the FBG and AMS in both groups were significantly improved, and the improvement in the observation group was significantly better than that in the control group. There was no statistical difference between the two groups before treatment (SOD, CAT, MDA and GSH-PX) (P> 0.05). After treatment, the above indexes were significantly improved, and the improvement of the observation group was better than the control group, and the oxygenation index improved better than the control group, the difference was statistically significant (P <0.05). Conclusion: Continuous blood purification treatment for patients with severe pancreatitis has important application value.