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双硫仑是一种戒酒药物,服用该药后即使饮用少量的酒或含乙醇的饮料,身体也会产生严重不适,引起双硫仑样反应。抗菌药物中许多品种具有与双硫仑相似的作用,服用这类药物后饮酒或服用含有乙醇的药物或饮品,甚至皮肤接触乙醇,均可导致“乙醛蓄积”的中毒反应。本文对3例服用抗菌药物后饮酒及药酒等导致双硫仑样反应进行了分析,并提出了预防双硫样反应的措施建议。
Disulfiram, a drug for abstinence, causes severe discomfort in the body even after drinking a small amount of alcohol or alcohol-containing beverages, causing a disulfiram-like reaction. Many varieties of antimicrobial drugs have a similar effect to that of disulfiram. Drinking these drugs after drinking or taking alcohol-containing drugs or drinks, or even skin-contact with ethanol, can lead to poisoning of acetaldehyde accumulation. In this paper, three cases of anti-bacterial drug consumption led to disulfiram-like reactions were analyzed, and proposed measures to prevent the dithio-like reaction.