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增殖细胞核抗原(proliferatingcellnuclearantigen,PCNA)是一种与细胞增殖周期有关的标志物,其表达状况与肿瘤细胞增殖活性相关。采用抗PCNA单克隆抗体(mAb)定位和定量研究其表达,可作为判断细胞增殖情况及预后的一种手?
Proliferating cell nuclear antigen (PCNA) is a marker associated with cell proliferation cycle, and its expression status is related to the proliferation activity of tumor cells. The use of anti-PC NA monoclonal antibody (mAb) localization and quantitative study of its expression can be used as a hand to determine cell proliferation and prognosis.