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对四川省1958~1996年的钩体病流行情况进行了分析。39年来,全省84.01%的县有病例报告,累计发病677403例,年均发病率为19.49/10万,死亡7588人,年均病死率为1.12%。流行形式以“稻田型”为主;感染方式主要以收割水稻接触疫水而感染。发病高峰为每年8~9月,青壮年农民发病最多,男与女之比为1.90∶1。经过疫源地调查,已从28种动物中分离出钩体。啮齿和食虫动物为“稻田型”钩体的主要传染源;家畜为“洪水型”钩体主要传染源。全省流行菌群有17群,以黄疸群为主,占66.36%。有39个血清型,其中赖型占53.99%。各地流行菌群菌型基本稳定,但不同地区和年代亦有变化。钩体病流行强度与宿主动物数量、带菌率高低、人群免疫水平、水稻收割季节、降雨量密切相关。
The prevalence of leptospirosis in Sichuan from 1958 to 1996 was analyzed. In the past 39 years, 84.01% of the counties in the province have reported cases with a cumulative incidence of 677,403 cases, with an average annual incidence rate of 19.49 per 100,000 and 7588 deaths, with an average annual mortality rate of 1.12%. The popular form is “paddy field type”; the infection mode is mainly infected by the contact of the harvested rice with the infected water. Peak incidence of 8 to 9 per year, most young farmers incidence, male to female ratio of 1.90: 1. After investigation of the foci, hook bodies have been isolated from 28 species of animals. Rodents and carnivores were the main source of infection of “paddy-type” leptospira; livestock was the main source of infection of “flood-type” leptospira. The province has 17 groups of popular flora, jaundice group, accounting for 66.36%. There are 39 serotypes, of which accounted for 53.99%. The prevalence of endemic bacteria around the basically stable, but also different regions and age changes. The prevalence of leptospirosis is closely related to the number of host animals, the carrying rate, population immunity level, rice harvesting season and rainfall.