UPPP手术治疗肥胖引起的阻塞性睡眠呼吸暂停低通气综合征的疗效观察

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目的观察手术治疗肥胖引起的阻塞性睡眠呼吸暂停低通气综合征(OSAHS)的疗效,探索有效的治疗方法。方法对25例肥胖合并OSAHS患者手术前、UPPP(悬雍垂咽腭成形术)手术2年后行多导睡眠监测(PSG)。(对照组)29例肥胖合并OSAHS患者应用持续正压通气(CPAP)或者双水平持续正压通气(BIPAP)呼吸机治疗,并对治疗前、后2~3年行多导睡眠监测(PSG),对相关数据进行统计学处理。结果手术组治疗后25例仍有睡眠呼吸障碍及低氧血症,治疗前后对比P>0.05。呼吸机组(对照组)无睡眠呼吸障碍及低氧血症。治疗前后对比P<0.01。组间比较P<0.01。结论对单纯肥胖引起的OSAHS手术治疗无效或者效果差,不主张常规手术。无创呼吸机或者减轻体质量是治疗单纯肥胖引起的OSAHS的有效方法。 Objective To observe the efficacy of surgical treatment of obstructive sleep apnea-hypopnea syndrome (OSAHS) caused by obesity and to explore effective treatment. Methods Polysomnography (PSG) was performed 2 years after UPPP (Uvulopalatopharyngoplasty) surgery in 25 patients with obesity and OSAHS. (Control group) 29 patients with obesity and OSAHS were treated with continuous positive airway pressure (CPAP) or bipolar Bipolar Ventilator (BIPAP) ventilator and polysomnography (PSG) was performed before and 2 to 3 years after treatment. , The relevant data for statistical analysis. Results In the operation group, 25 patients still had sleep-disordered breathing and hypoxemia after treatment, with a significant difference between before and after treatment (P> 0.05). Breathing machine (control group) without sleep disordered breathing and hypoxemia. Before and after treatment, P <0.01. Comparison between groups P <0.01. Conclusion OSAHS surgery alone caused by obesity is ineffective or ineffective, not advocating conventional surgery. Non-invasive ventilator or reduce body mass is an effective method of treatment of OSAHS caused by simple obesity.
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