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目的探讨住院患者抗生素类药物的使用情况。方法选取2014年1—12月在长春市双阳区医院就诊的3512例住院患者,将其中使用过抗生素的2374例患者作为研究对象,对使用抗生素患者的基本资料进行询问和记录,包括姓名、性别、年龄和病因等,将每例患者使用抗生素的种类、剂量、联合用药等情况进行详细记录,统计并分析其各类抗生素的使用情况及联合用药情况。结果住院患者抗生素使用率为67.6%(2374/3512);在抗生素的使用中,使用率最高的为头孢菌素类,其次是氟喹诺酮类;2374例患者中,单一使用抗生素(一联用药)828例,占34.9%(828/2374);二联用药994例,占41.9%(994/2374);3联用药552例,占23.3%(552/2374)。结论全年中有超过一半以上的患者使用抗生素,其使用率最高的为头孢菌素类,且二联用药率较高,针对其不合理用药情况,应严格按照国家制定的用药规范进行合理使用抗生素,确保患者能够安全用药。
Objective To investigate the use of antibiotics in hospitalized patients. Methods A total of 3512 hospitalized patients in Shuangyang District Hospital of Changchun from January to December 2014 were enrolled in this study. 2374 patients with antibiotics were enrolled in this study. The basic data of patients with antibiotics were asked and recorded, including name, sex , Age and cause of each patient, the type of antibiotic used in each patient, dose, combined with detailed records of such cases, statistics and analysis of the use of various types of antibiotics and combined use of drugs. Results The antibiotic use rate in hospitalized patients was 67.6% (2374/3512). Among the antibiotics, the highest utilization rate was cephalosporins followed by fluoroquinolones. Among the 2374 patients, antibiotics were used alone (one combination) 828 cases, accounting for 34.9% (828/2374); 994 cases of second-line drugs, accounting for 41.9% (994/2374); and 552 cases of 3-drug combination, accounting for 23.3% (552/2374). Conclusions More than half of the patients in the whole year use antibiotics. The most frequently used antibiotics are cephalosporins, and the rate of drug use in the two groups is high. In view of their irrational drug use, they should be used reasonably in accordance with the national drug regulations Antibiotics, to ensure that patients can safely medication.