血浆D-二聚体是纤溶酶水解交联纤维蛋白形成的降解产物之一,为继发性纤溶特有的代谢物,其含量变化可作为体内高凝状态和原发性与继发性纤溶鉴别的可靠指标,也可作为溶栓治疗有效性的观察指标。近年来,D-二聚体检测在临床得到新的应用,尤其对心房颤动患者血栓的诊断。现就血浆D-二聚体检测及其对心房颤动患者血栓诊断的研究进展予以综述。 Plasma D-dimer is one of the degradation products of fibrinolytic cross-linked fibrin. It is a specific metabolite of secondary fibrinolysis, and its content change can be used as hypercoagulable state in vivo and primary and secondary Fibrinolytic reliable indicators, but also as an effective indicator of thrombolytic therapy. In recent years, D-dimer test in the clinical application of new, especially for the diagnosis of thrombus in patients with atrial fibrillation. Now on the plasma D-dimer test and its diagnosis of atrial fibrillation in patients with thrombosis are reviewed.