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目的掌握胃肠道炎性纤维性息肉(IFP)的诊断和鉴别诊断。方法观察9例IFP临床、病理改变及免疫组织化学(ABC)标记。结果IFP是发生在胃肠道粘膜下,向腔内突出的息肉样肿块。以纤维血管增生伴数量不等的炎症细胞,特别是嗜酸性粒细胞浸润,纤维母细胞略呈车辐状排列,可围绕血管呈葱皮样改变为其组织学特征。免疫组织化学标记表达Vimentin(9/9),SMA(6/9)。结论IFP可能是对感染或其它原因损伤的过度反应,节段切除、内窥镜下摘除预后良好。
Objective To master the diagnosis and differential diagnosis of inflammatory fibrous polyposis (IFP) in the gastrointestinal tract. Methods The clinical, pathological changes and immunohistochemistry (ABC) markers of 9 cases of IFP were observed. Results IFP is a polypoid mass that protrudes from the gastrointestinal mucosa and protrudes into the lumen. Fibroblast proliferation with varying amounts of inflammatory cells, especially eosinophil infiltration, fibroblasts arranged slightly in a car-like arrangement, can be changed to histological characteristics around the blood vessels onion. Immunohistochemical markers express Vimentin (9/9), SMA (6/9). Conclusions IFP may be an overreaction to infection or other causes of injury. Segmental resection and endoscopic removal have a good prognosis.