论文部分内容阅读
目的对广州市2011年9月至2012年2月100 452例新生儿先天性甲状腺功能低下症筛查的情况进行分析和总结,了解我市新生儿CH的筛查情况和发病率。方法利用荧光酶免疫方法对2011年9月-2012年2月广州市出生的新生儿进行足底血片TSH筛查,筛查阳性患儿召回测定TSH、FT3、FT4作出诊断。结果 2011年9月至2012年2月共筛查100 452例,确诊CH49例,发病率为1/2050,高TSH血症7例,发病率1/14 350。结论先天性甲状腺功能减低症因其出生时没有或很少有甲低的症状和体征容易误诊,在新生儿期对其进行筛查可以减少误诊率,使患儿得到早期诊断和治疗,防止症状的发生和发展,避免发生不可逆的智能障碍,各医疗保健机构应加强新生儿筛查工作,进一步提高筛查覆盖率,降低CH患儿残疾发病率,提高出生人口素质。
Objective To analyze and summarize the screening of 100 452 neonates with congenital hypothyroidism from September 2011 to February 2012 in Guangzhou to find out the screening status and incidence of neonatal CH in our city. Methods Fluorescein immunization method was used to screen TSH screening of newborns born in Guangzhou from September 2011 to February 2012, and TSH, FT3 and FT4 were screened in the positive children for screening. Results From September 2011 to February 2012, a total of 100 452 cases were screened, 49 cases were diagnosed as CH49, the incidence was 1/2050 and 7 cases were hypercholesteremia. The incidence was 1/14 350. Conclusions Congenital hypothyroidism is easily misdiagnosed because of its low or no hypothyroidism at birth. Screening in neonatal period can reduce the rate of misdiagnosis, make early diagnosis and treatment and prevent symptoms Occurrence and development of HIV / AIDS prevention and treatment to avoid irreversible mental retardation. All health care institutions should strengthen neonatal screening to further improve screening coverage, reduce the incidence of disability in children with CH, and improve the quality of the birth population.